MUSCLE PHYSIOLOGY

Detailed explanation-1: -2 molecules of ATP are utilised in the glycolysis. One molecule of ATP is utilised when glucose is converted to glucose-6-phosphate and the other is utilised when fructose-6-phosphate is converted to fructose-1, 6-bisphosphate . So, the net gain of ATP molecules during glycolysis is 2.

Detailed explanation-2: -Glycolysis produces only two net molecules of ATP per 1 molecule of glucose. However, in cells lacking mitochondria and/or adequate oxygen supply, glycolysis is the sole process by which such cells can produce ATP from glucose.