PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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4 ATP, 2 NADH, and 2 pyruvate
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4 ATP, 2 NADH, and 4 pyruvate
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2 ATP, 2 NADH, and 2 pyruvate
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2 ATP, 1 NADH, and 1 pyruvate
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Detailed explanation-1: -During glycolysis, glucose ultimately breaks down into pyruvate and energy; a total of 2 ATP is derived in the process (Glucose + 2 NAD+ + 2 ADP + 2 Pi–> 2 Pyruvate + 2 NADH + 2 H+ + 2 ATP + 2 H2O).
Detailed explanation-2: -One glucose molecule yields four ATP molecules in total during glycolysis. Since 2 ATP molecules are used up in the first phase of glycolysis, there is a net gain of 2 ATP molecules. In addition, glycolysis results in the production of 2 NADH molecules.
Detailed explanation-3: -2 molecules of ATP are utilised in the glycolysis. One molecule of ATP is utilised when glucose is converted to glucose-6-phosphate and the other is utilised when fructose-6-phosphate is converted to fructose-1, 6-bisphosphate. So, the net gain of ATP molecules during glycolysis is 2.