PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Inner mitochondrial membrane
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Cytoplasm
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Mitochondrial matrix
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Outer mitochondrial matrix
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Detailed explanation-1: -The link reaction occurs in the mitochondrial matrix. It dehydrogenates and decarboxylates the three-carbon pyruvate to produce the two-carbon acetyl CoA that can enter the Krebs Cycle.
Detailed explanation-2: -Aerobic respiration commences with the oxidation of pyruvic acid. This is called link reaction or gateway step as it links glycolysis in cytoplasm and Krebs cycle in mitochondrial matrix.
Detailed explanation-3: -According to Model 2, where in a cell does the link reaction take place? In the inner matrix of the mitochondria. 10. Consider the pyruvate molecule.
Detailed explanation-4: -There is the formation of acetate which binds with CoA to form acetyl-CoA. NAD molecule is reduced to form NADH. It takes place in the presence of enzyme pyruvate dehydrogenase. This reaction is known as the connecting link between glycolysis and Krebs cycle.