MUSCLE PHYSIOLOGY

Detailed explanation-1: -NAD+ to NADH transformation When NAD+ takes an electron from glucose, it becomes NADH, the reduced form of the molecule. NADH transports this electron to mitochondria where the cell can take the energy that is stored in the electron. NADH then donates the electron to oxygen, converting it back to NAD+.

Detailed explanation-2: -Reduction of NADH dehydrogenase activity leads to reduced rates of NADH reduction; thus, less hydrogen ions contribute to the polarity of the mitochondrial membrane and decreased rates of electron binding to ubiquinone.