MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE ENERGETICS GLYCOLYSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following processes in glycolysis is not reversible?
A
3-phosphoglycerate to 2-phosphoglycerate
B
fructose-6-phosphate to fructose 1, 6 bisphosphate
C
glyceraldehyde-3-phosphate to 1, 3-bisphosphoglycerate
D
glucose-6-phosphate to fructose-6-phosphate
Explanation: 

Detailed explanation-1: -At this stage fructose 1, 6-bisphosphate is cleaved to give two triose phosphate molecules, namely glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in a reversible reaction which is catalysed by aldolase.

Detailed explanation-2: -The reactions of glycolysis convert glucose 6-phosphate to pyruvate. The entire process is cytosolic. Glucose 6-phosphate is reversibly isomerized to form fructose 6-phosphate.

Detailed explanation-3: -This is one of two energy consumption steps and is an irreversible reaction. Next, an isomerase reaction converts glucose-6-phosphate into fructose-6-phosphate by rearranging covalent bonds. Another kinase removes a phosphate group from ATP and gives it to fructose-6-phosphate to form fructose-1, 6-bisphosphate.

There is 1 question to complete.