PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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phosphoenolpyruvate to pyruvate
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fructose 6-phosphate to fructose 1, 6-bisphosphate
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glucose to glucose 6-phosphate
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glyceraldehyde 3 phosphate to fructose 1, 6-bisphosphate
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Detailed explanation-1: -Most of the enzymes required for gluconeogenesis are the same ones in glycolysis. 3 irreversible steps in glycolysis: hexokinase; phosphofructokinase; pyruvate kinase.
Detailed explanation-2: -So the correct answer should be option “Triose phosphate mutase"
Detailed explanation-3: -Regulation of glycolysis occurs at three points of the pathway. These correspond to the steps with the largest negative free energy changes (i.e. most exergonic-negative G). The magnitude of the G for these steps makes them essentially irreversible.
Detailed explanation-4: -The enzyme Hexokinase is known to catalyze the conversion of glucose to glucose-6-phosphate. It is an irreversible reaction and requires ATP. It is a part of glycolysis.