PHYSIOLOGY
MUSCLE FATIGUE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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L-lactate
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Lactic acidosis
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D-lactate
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None of the above
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Detailed explanation-1: -Lactic acid exists in the form of two enantiomers: D-lactic acid and L-lactic acid.
Detailed explanation-2: -Lactic acid exists in two optical isomeric forms, L-lactate and D-lactate. L-lactate is the most commonly measured level, as it is the only form produced in human metabolism.
Detailed explanation-3: -D-Lactic acid is the end product of the enzyme Glyoxalase II ([EC:3.1. 2.6] hydroxyacyl-glutathione hydrolase) which converts the intermediate substrate S-lactoyl-glutathione to reduced glutathione and D-lactate. (OMIM 138790). The concentrated form is used internally to prevent gastrointestinal fermentation.
Detailed explanation-4: -D-lactic acidosis is an unusual form of lactic acidosis that can occur in patients with short bowel syndrome. It has also been described in patients who receive or ingest large amounts of propylene glycol and in patients with diabetic ketoacidosis.
Detailed explanation-5: -lactic acid, also called -hydroxypropionic acid, or 2-hydroxypropanoic acid, an organic compound belonging to the family of carboxylic acids, present in certain plant juices, in the blood and muscles of animals, and in the soil.