MUSCLE PHYSIOLOGY

Detailed explanation-1: -2 adrenergic agonists’ effects on smooth muscle cause dilation of bronchial passages, vasodilation in muscle and liver, relaxation of uterine muscle, and release of insulin. They are primarily used to treat asthma and other pulmonary disorders, such as Chronic obstructive pulmonary disease (COPD).

Detailed explanation-2: -Albuterol and salmeterol stimulate Beta 2-adrenergic receptors in the smooth muscle of bronchi and bronchioles producing bronchodilation. Beta-1 receptors can also be inadvertently stimulated, causing tachycardia.

Detailed explanation-3: -Activation of vascular beta 2 adrenergic receptors causes vasodilatation through endothelium-dependent and-independent mechanisms.