PHYSIOLOGY
MYASTHENIA GRAVIS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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There is purpura on the arms and legs
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Anaphylactic shock occurs during strenuous activity
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Abnormal and progressive weakness of the skeletal muscles
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Cramps in the extremities
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Keratin deficiency
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Detailed explanation-1: -Weakness of the eye muscles (ocular myasthenia) Drooping of one or both eyelids (ptosis) Blurred or double vision (diplopia) Changes in facial expressions. Difficulty swallowing. Shortness of breath. Impaired speech (dysarthria) More items •23-Jan-2023
Detailed explanation-2: -In myasthenia gravis, your immune system produces antibodies that block or destroy many of your muscles’ receptor sites for a neurotransmitter called acetylcholine (as-uh-teel-KOH-leen). With fewer receptor sites available, your muscles receive fewer nerve signals, resulting in weakness.
Detailed explanation-3: -Myasthenic crisis is a complication of myasthenia gravis characterized by worsening of muscle weakness, resulting in respiratory failure that requires intubation and mechanical ventilation. Advances in critical care have improved the mortality rate associated with myasthenic crisis.
Detailed explanation-4: -Droopy eyelids or double vision is the most common symptom at initial presentation of MG, with more than 75% of patients. These symptoms progress from mild to more severe disease over weeks to months. Difficulty in swallowing, slurred or nasal speech, difficulty chewing, and facial, neck, and extremity weakness occur.