MUSCLE PHYSIOLOGY

Detailed explanation-1: -The postsynaptic part of the motor endplate is positioned on the receiving end of the synaptic cleft. As already mentioned, this membrane is folded. These folds are called subneural clefts and are necessary to increase the surface area of the synapse.

Detailed explanation-2: -Free acetylcholine within the synaptic cleft is degraded by an enzyme called acetylcholinesterase. This enzyme assures that no excess of acetylcholine remains in the synaptic cleft to cause the continuous activation of receptors. Acetylcholine has different roles and functions at different synapses throughout the body.