PHYSIOLOGY
NEUROMUSCULAR JUNCTION TRANSMISSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is required to detach the cross-bridges from actin?
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ATP to bind actin
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ATP to bind myosin heads
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Calcium to be released
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None of the above
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Explanation:
Detailed explanation-1: -ATP binding causes myosin to release actin, allowing actin and myosin to detach from each other. After this happens, the newly bound ATP is converted to ADP and inorganic phosphate, Pi. The enzyme at the binding site on myosin is called ATPase.
Detailed explanation-2: -After myosin changes its shape, ATP binds to the myosin head. That binding of ATP to myosin releases the myosin from actin, and that changes the cross-bridge to its detached state.
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