PHYSIOLOGY
NEUROMUSCULAR JUNCTION TRANSMISSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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An AP reaches the Kronocyte.
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An AP reaches the presynaptic terminal of the NMJ.
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Ach vesicle migration and fusion
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End plate potential
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Detailed explanation-1: -The five important steps in the process of neuromuscular transmission are as follows: 1. Acetylcholine release – When an action potential reaches an axon terminal, it opens voltage-gated calcium channels in the axon terminal’s membrane.
Detailed explanation-2: -Steps of Signalling at Neuromuscular Junctions Firstly, the signal from the axon terminal of the previous neuron travels down the motor neuron to the presynaptic axon terminal. This causes the activation and opening of calcium channels in the membrane, allowing calcium ions to enter the neuron.
Detailed explanation-3: -When an action potential reaches a neuromuscular junction, it causes acetylcholine to be released into this synapse. The acetylcholine binds to the nicotinic receptors concentrated on the motor end plate, a specialized area of the muscle fibre’s post-synaptic membrane.
Detailed explanation-4: -Answer and Explanation: During the transmission of signals across a neuromuscular junction, the first thing to happen is synaptic vesicles move toward the axon terminals (d is correct).
Detailed explanation-5: -The motor nerve forwards an impulse along its axon until it reaches the axon’s end. This action potential opens calcium ion channels at the end of the axon. Calcium ions flow into the motor nerve cell. Intracellular calcium sends vesicles to the edge of the presynaptic membrane. More items •17-Apr-2021