PHYSIOLOGY
NEUROMUSCULAR JUNCTION TRANSMISSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Acetylcholine
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Acetone
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ATP
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Calcium
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Detailed explanation-1: -In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma.
Detailed explanation-2: -Cholinergic neurons that release acetylcholine, an excitatory neurotransmitter, are widely distributed in the central nervous system.
Detailed explanation-3: -The release of acetylcholine occurs when an action potential is relayed and reaches the axon terminus in which depolarization causes voltage-gated calcium channels to open and conduct an influx of calcium, which will allow the vesicles containing acetylcholine for release into the synaptic cleft.