MUSCLE PHYSIOLOGY

PHYSIOLOGY

SARCOMERE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The crossbridges involved in muscle contraction are located on the ____
A
myosin filaments
B
actin filaments
C
tropomyosin
D
troponin
Explanation: 

Detailed explanation-1: -The myosin heads are known as cross-bridges because they can bind to and move along actin in the thin filament . It is this actin-myosin interaction that is the molecular basis for force generation and movement in muscle cells.

Detailed explanation-2: -Cross-bridges at various angles are seen between the thick and thin filaments binding in the actin target zones at 38.7-nm axial intervals on the thin filaments. Some cross-bridges are also seen binding in between the target zones.

Detailed explanation-3: -Force generation in the muscle sarcomere is driven by the head domain of the myosin molecule extending from the thick filament to form cross-bridges with the actin-containing thin filament.

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