MUSCLE PHYSIOLOGY

Detailed explanation-1: -The troponin complex, together with tropomyosin and Ca2 + ions, plays a central role in the regulation of thin myofilament contraction and relaxation in striated cardiac and skeletal muscle tissues.

Detailed explanation-2: -Troponin complex is a component of skeletal and cardiac muscle thin filaments. It consists of three subunits-troponin I, T, and C, and it plays a crucial role in muscle activity, connecting changes in intracellular Ca2+ concentration with generation of contraction.

Detailed explanation-3: -Troponin T (TnT) binds to tropomyosin (Tm) to anchor the troponin complex in the thin filament, and it thus serves as a vital link in the Ca2+ regulation of striated muscle contraction.

Detailed explanation-4: -Troponin and tropomyosin are two proteins that are present on the thin filaments of the muscle cells and help in the contraction of muscles. However, they have opposite functions. While troponin promotes muscle contraction, tropomyosin blocks muscle contraction.