MUSCLE PHYSIOLOGY

PHYSIOLOGY

SARCOMERE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What protein helps the sarcomere to “rebound” after a contraction?
A
Titin
B
Nebulin
C
Tropomyosin
D
Myosin
Explanation: 

Detailed explanation-1: -The two largest proteins in the sarcomere, nebulin and titin, help link the actin and myosin filaments in the sarcomere.

Detailed explanation-2: -Titin is a huge, 4.2 MDa, filamentous protein located in the sarcomere of striated muscle. Extending from its N-terminus anchored in the Z-disc to its C-terminus bound to thick filaments in the M-band, titin is largely responsible for the passive stiffness of the myocardium exhibited during diastolic filling.

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