MUSCLE PHYSIOLOGY

PHYSIOLOGY

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Once started, the action potential cannot be stopped, and contraction occurs
A
True
B
False
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -The falling phase of the action potential is caused by the inactivation of the sodium channels and the opening of the potassium channels. After approximately 1 msec, the sodium channels inactivate. The channel becomes blocked, preventing ion flow.

Detailed explanation-2: -The action potential invades T-tubules and causes the L-type calcium channels to open, which in turn causes ryanodine receptors (RyRs) in the SR to open and release calcium, which stimulates contraction.

There is 1 question to complete.