MUSCLE PHYSIOLOGY

PHYSIOLOGY

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The mechanical force of contraction is generated by:
A
shortening of the thick filaments
B
the “accordian-like” folding of think and thick filaments
C
a sliding of thin filaments past thick ones
D
the temporary disappearance of thin filaments
Explanation: 

Detailed explanation-1: -The most popular model that describes muscular contraction is called the sliding filament theory . In this theory, active force is generated as actin filaments slide past the myosin filaments, resulting in contraction of an individual sarcomere.

Detailed explanation-2: -This process is known as myosin-actin cycling. As the myosin S1 segment binds and releases actin, it forms what are called cross bridges, which extend from the thick myosin filaments to the thin actin filaments. The contraction of myosin’s S1 region is called the power stroke (Figure 3).

Detailed explanation-3: -Actin filaments, usually in association with myosin, are responsible for many types of cell movements. Myosin is the prototype of a molecular motor-a protein that converts chemical energy in the form of ATP to mechanical energy, thus generating force and movement.

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