MUSCLE PHYSIOLOGY

PHYSIOLOGY

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What two structures are closely associated at a neuromuscular junction?
A
nerves and muscle
B
neurons and blood cells
C
bones and organs
D
blood vessel and the digestive system
Explanation: 

Detailed explanation-1: -For convenience and understanding, the structure of NMJ can be divided into three main parts: a presynaptic part (nerve terminal), the postsynaptic part (motor endplate), and an area between the nerve terminal and motor endplate (synaptic cleft).

Detailed explanation-2: -The space between the nerve terminal and the motor endplate on the plasma membrane of muscle is called the synaptic/junctional cleft and measures ∼50 nm. It is the site where presynaptic neurotransmitters, ACh is released before it interacts with nicotinic ACh receptors on the motor endplate.

Detailed explanation-3: -The neuromuscular junction is composed of three major structures. The presynaptic vesicles, the synaptic cleft, sometimes called the synaptic junction, and the postsynaptic membrane of the skeletal muscle cell containing neurotransmitter receptors.

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