PHYSIOLOGY
SKELETAL MUSCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Release energy through the breakdown of ATP
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Form cross-bridges with the active sites on actin molecules
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Produce tropomyosin to facilitate binding to actin molecules
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Bend and straighten during contraction due to the hinge attaching it to the rod portion
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Detailed explanation-1: -Myosins are the molecular motors best known for powering muscle contraction, but nonmuscle isoforms serve as intracellular cargo transporters, cytoskeletal anchors, and signaling molecules.
Detailed explanation-2: -Tropomyosin binds along actin filaments and regulates actin-myosin interaction in muscle and nonmuscle cells. Seven periodic amino acid repeats are proposed to correspond to actin binding sites, and the middle periods are important for cooperative activation of actin by myosin.
Detailed explanation-3: -The motion of muscle shortening occurs as myosin heads bind to actin and pull the actin inwards. This action requires energy, which is provided by ATP. Myosin binds to actin at a binding site on the globular actin protein.