PHYSIOLOGY
SLIDING FILAMENT MODEL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Calcium
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causes ATP binding to actin
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increases the action potential along the sarcolemma
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binds to proteins on myosin
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triggers the binding of myosin to actin
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Explanation:
Detailed explanation-1: -In striated muscle, calcium causes a shift in the position of the troponin complex on actin filaments, which exposes myosin-binding sites (Fig. 2A). Myosin bound by ADP and inorganic phosphate (Pi) can then form cross-bridges with actin, and the release of ADP and Pi produces the power stroke that drives contraction.
Detailed explanation-2: -Calcium diffusing in the cytoplasm between myosin and actin filaments of the muscle fibrils causes the filaments to slide into each other, triggering the contraction of the entire muscle fiber.
Detailed explanation-3: -In skeletal or cardiac muscles, actin filaments are also associated with troponin, 8) which is a calcium-binding protein that regulates contraction.
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