PHYSIOLOGY
SLIDING FILAMENT MODEL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A description of the shapes of muscles
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A theory explaining that lengthening the sarcomeres causes a muscle to move
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An explanation for how muscle contraction occurs
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A description of how myosin filaments move.
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Detailed explanation-1: -According to the sliding filament theory, muscle contraction occurs through the relative sliding of two sets of filaments (actin and myosin). This sliding is produced by cyclic interactions of sidepieces from the myosin filament (cross-bridges) with specific sites on the actin filament.
Detailed explanation-2: -By studying sarcomeres, the basic unit controlling changes in muscle length, scientists proposed the sliding filament theory to explain the molecular mechanisms behind muscle contraction. Within the sarcomere, myosin slides along actin to contract the muscle fiber in a process that requires ATP.
Detailed explanation-3: -Cross-bridge mechanism With substantial evidence, Hugh Huxley formally proposed the mechanism for sliding filament which is variously called swinging cross-bridge model, cross-bridge theory or cross-bridge model.