GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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They only increase expression
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They only decrease expression
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They interact with RNA polymerase but do not affect the expression
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They can act both as activators and as repressors
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Detailed explanation-1: -Final answer: d. They can act both as activators and as repressors.
Detailed explanation-2: -In a transcription unit of prokaryotes, the activity of RNA polymerase at a given promoter is regulated by interaction with accessory proteins called regulatory proteins which affect its ability to recognise start sites. These regulatory proteins can act both positively (activators) and negatively (repressors).
Detailed explanation-3: -Transcription factors (TFs) are regulatory proteins whose function is to activate (or more rarely, to inhibit) transcription of DNA by binding to specific DNA sequences.
Detailed explanation-4: -Which of the following statements is correct about the role of regulatory proteins in transcription in prokaryotes ? Solution : They can act both as activators and as repressors Regulatory proteins are the accessory proteins that interact with RNA polymerase and affect its role in transcription.
Detailed explanation-5: -There are also well known examples of vesicle-associated regulatory proteins, such as Ire1 and SREBP, that control responses closely tied to vesicle properties or function (2, 3).