NURSING ANM AND GNM

Detailed explanation-1: -GLUT4 is an insulin-responsive glucose transporter that is found in the heart, skeletal muscle, adipose tissue, and brain. It is present in the cytoplasm of cells in vesicles from which it is translocated to the plasma membrane under the influence of insulin.

Detailed explanation-2: -Glucose enters the beta cells of the pancreas through the glucose transporter GLUT2 and this is a major signal leading to the release of insulin from these cells that reaches the bloodstream.

Detailed explanation-3: -Glucose uptake in muscle occurs by a system of facilitated diffusion involving at least two distinct glucose transporters, GLUT-1 and GLUT-4.