NURSING ANM AND GNM

NURSING EXAM QUESTIONS

BIOCHEMISTRY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In HMP shunt first 3 steps are ____
A
Oxidative pathway
B
Non-oxidative pathway
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -The three steps of the oxidative phase of the HMP shunt are: Glucose-6-phosphate is dehydrogenated to 6-phosphoglucono--lactone in the presence of glucose 6-phosphate dehydrogenase. In this reaction, one molecule of NADP+ is converted into NADPH.

Detailed explanation-2: -To summarize, the oxidative phase of the pentose phosphate pathway oxidizes a glucose 6-phosphate into a ribose 6-phosphate while in the process generated two NADPH molecules, a carbon dioxide and 2 H+ ions.

Detailed explanation-3: -The hexose monophosphate shunt (HMP) is also called the pentose phosphate pathway. It occurs in the cytoplasm and is a major source of NADPH and 5-carbon sugars. The HMP consists of two irreversible oxidative reactions and a series of reversible sugar-phosphate conversions.

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