NURSING ANM AND GNM

Detailed explanation-1: -The net product of the glyoxylate cycle is succinate, which can be used to replenish TCA cycle intermediates or to generate metabolites for gluconeogenesis and other biosynthetic processes. Thus, the glyoxylate cycle provides an effective route for growth on fatty acids and C2 compounds such as acetate and ethanol.

Detailed explanation-2: -The glyoxylate cycle, a variation of the tricarboxylic acid cycle, is an anabolic pathway occurring in plants, bacteria, protists, and fungi. The glyoxylate cycle centers on the conversion of acetyl-CoA to succinate for the synthesis of carbohydrates.

Detailed explanation-3: -The glyoxylate cycle, also called the glyoxylate shunt, is present in fungi, plants, and bacteria, but not in mammals. The cycle is essential for growth on two-carbon compounds such as ethanol and acetate, and plays an anaplerotic role in the provision of precursors for biosynthesis.

Detailed explanation-4: -Abstract. Key enzymes of the glyoxylate cycle, isocitrate lyase (ICL) and malate synthase (MS), have been detected in the liver of alloxan-treated rats.