NURSING EXAM QUESTIONS
BIOCHEMISTRY
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Hexokinase (HK)
|
|
|
Triose phosphate isomerase (TIM)
|
|
|
Phosphoglycerate kinase (PGK)
|
|
|
Phosphofructokinase (PFK)
|
Detailed explanation-1: -Hexokinase is the initial enzyme of glycolysis, catalyzing the phosphorylation of glucose by ATP to glucose-6-P.
Detailed explanation-2: -So the correct answer is ‘Hexokinase’.
Detailed explanation-3: -The enzyme phosphogluco isomerase converts glucose-6-phosphate into fructose-6-phosphate.
Detailed explanation-4: -Explanation: The rate-limiting step of glycolysis is the conversion of glucose-6-phosphate to fructose-6-phosphate. This reaction is catalyzed by the enzyme phosphofructokinase.
Detailed explanation-5: -Hexokinase is the first enzyme in the glycolytic pathway, and it converts glucose into glucose-6-phosphate. It uses ATP to phosphorylate the 6-hydroxyl group of glucose, and it is inhibited by its product, glucose-6-phosphate. It is also allosterically relieved of product inhibition by phosphate.