NURSING ANM AND GNM

Detailed explanation-1: -In the lock-and-key model, the enzyme-substrate interaction suggests that the enzyme and the substrate possess specific complementary geometric shapes that fit exactly into one another.

Detailed explanation-2: -A Lock and Key analogy may be used to describe the fundamental action of a single substrate enzyme. In this case, the enzyme is the lock, and the substrate is the key. Only the correct size key, which is the substrate, enters the keyhole, which is the active site of the lock, which is the enzyme.

Detailed explanation-3: -The theory was postulated by Emil Fisher in 1898. According to the hypothesis, like a lock can be open by its key only, a substance possessing specific composition only can combine with the specific active site found in the specific enzyme’s surface.

Detailed explanation-4: -The catalytic cycle helps to explain the mechanism of enzyme action through the following points: The substrate gets bound to the active site. This induces an alteration in the shape of the enzyme. The enzyme-product complex is formed by making and breaking bonds.

Detailed explanation-5: -enzymes. …and enzyme, called the “key–lock” hypothesis, was proposed by German chemist Emil Fischer in 1899 and explains one of the most important features of enzymes, their specificity.