NURSING ANM AND GNM

Detailed explanation-1: -The first model called the lock and key model, proposes that the shape and chemistry of the substrate are complementary to the shape and chemistry of the active site on the enzyme. This means when the substrate enters the active site, it fits perfectly, and the two binds together, forming the enzyme-substrate complex.

Detailed explanation-2: -Enzymes are specific to substrates as they have an active site which only allow certain substrates to bind to the active site. This is due to the shape of the active site and any other substrates cannot bind to the active site.

Detailed explanation-3: -The enzyme and its substrate must have complementary shapes to be able to fit together. In other words, they must fit together like jigsaw puzzle pieces. This means that enzymes will only operate on very specific substrates. Each enzyme, therefore, only catalyzes one specific reaction.

Detailed explanation-4: -Enzymes are proteins. Enzymes generally have a globular shape, and on their surface, there is a region called the active site. Each enzyme has a different, specifically shaped active site. This is because each type of enzyme is suited to one, or a few, particular molecules that will bind to it, called the substrates.

Detailed explanation-5: -Induced fit model Like a key into a lock, only the correct size and shape of the substrate (the key) would fit into the active site (the key hole) of the enzyme (the lock).