NURSING ANM AND GNM

Detailed explanation-1: -Substrates bind to the active site of the enzyme through hydrogen bonds, hydrophobic interactions, ionic bonding, temporary covalent interactions (Van der Waals’) or a combination of all of these to form the enzyme-substrate complex.

Detailed explanation-2: -The enzyme’s active site binds to the substrate. Since enzymes are proteins, this site is composed of a unique combination of amino acid residues (side chains or R groups).

Detailed explanation-3: -The substrate reversibly binds to the active site of the enzyme, forming the enzyme-substrate (ES) complex. The bound substrate is converted to product by catalytic groups in the active site, forming the enzyme-product complex (EP).