NURSING ANM AND GNM

Detailed explanation-1: -The endoplasmic reticulum (ER) is a network of membrane-enclosed tubules and sacs (cisternae) that extends from the nuclear membrane throughout the cytoplasm (Figure 9.1). The entire endoplasmic reticulum is enclosed by a continuous membrane and is the largest organelle of most eukaryotic cells.

Detailed explanation-2: -The endoplasmic reticulum (ER) is a membranous organelle that shares part of its membrane with that of the nucleus. Some portions of the ER, known as the rough ER, are studded with ribosomes and are involved with protein manufacture.

Detailed explanation-3: -Proteins are assembled at organelles called ribosomes. When proteins are destined to be part of the cell membrane or exported from the cell, the ribosomes assembling them attach to the endoplasmic reticulum, giving it a rough appearance.

Detailed explanation-4: -The rough endoplasmic reticulum has on it ribosomes, which are small, round organelles whose function it is to make those proteins.

Detailed explanation-5: -In eukaryotes, rough endoplasmic reticulum (RER) bear ribosomes on their surface. The attachment between ribosomes and endoplasmic reticulum is through a hydrophobic signal recognition particle or SRP linked to 60S subunit of ribosome and SRP receptor or ribophorin present over the ER.