NURSING ANM AND GNM

Detailed explanation-1: -The first model called the lock and key model, proposes that the shape and chemistry of the substrate are complementary to the shape and chemistry of the active site on the enzyme. This means when the substrate enters the active site, it fits perfectly, and the two binds together, forming the enzyme-substrate complex.

Detailed explanation-2: -In the lock and key model, the shape of the active site matches the shape of its substrate molecules. This makes enzymes highly specific – each type of enzyme can catalyse only one type of reaction (or just a few types of reactions).

Detailed explanation-3: -Why is shape important? The shape of an enzyme is very important because it has a direct effect on how it catalyzes a reaction. An enzyme’s shape is determined by the sequence of amino acids in its structure, and the bonds which form between the atoms of those molecules.

Detailed explanation-4: -(a) Because the substrate and the active site of the enzyme have complementary structures and bonding groups, they fit together as a key fits a lock.

Detailed explanation-5: -Enzymes are specific because different enzymes have differently shaped active sites. The shape of the active site of an enzyme is complementary to the shape of its specific substrate . This means they are the correct shapes to fit together. Temperature has an effect on enzyme activity.