NURSING ANM AND GNM

Detailed explanation-1: -Creatine kinase (CK) is an enzyme found in most tissues, and is the best known marker for the identification of acute myocardial infarction (AMI). We review the most common techniques used to quantify creatine kinase and its cardiac specific fraction, CK-MB.

Detailed explanation-2: -Elevated serum levels of CK–MB are therefore specific for myocardial cellular injury, but not for acute myocardial infarction. Following onset of symptoms of myocardial infarction CK and CK–MB increase in serum within 3 to 6 hours; the peak levels occur between 16 and 30 hours.

Detailed explanation-3: -This test helps your healthcare provider figure out if you’re having a heart attack. Measuring CK-MB used to be a common tool for diagnosing heart attacks, but healthcare providers use it less often today. Cardiac troponin is now the blood test of choice for finding a heart attack.

Detailed explanation-4: -Usually LDH isoenzyme levels increase 24–72 hours following myocardial infarction and reach a peak concentration in 3–4 days. The levels remain elevated for 8 to 14 days, making it a late marker for myocardial infarction.

Detailed explanation-5: -Damage to heart muscle cells causes CK-MB-as well as several other proteins and enzymes-to leak into your blood. This test can detect how much CK-MB enzyme is in your blood. If there’s more CK-MB in your blood than there should be, it can be a sign you’ve had a heart attack. CK-MB is also a time-sensitive test.