NURSING ANM AND GNM

Detailed explanation-1: -Serum creatinine is a more accurate assessment of renal function than urea; however, urea is increased earlier in renal disease. The ratio of BUN: creatinine can be useful to differentiate pre-renal from renal causes when the BUN is increased.

Detailed explanation-2: -The serum creatinine concentration is widely interpreted as a measure of the glomerular filtration rate (GFR) and is used as an index of renal function in clinical practice. Glomerular filtration of creatinine, however, is only one of the variables that determines its concentration in serum.

Detailed explanation-3: -Glomerular filtration rate (GFR): This test is a measure of how well the kidneys are removing wastes and excess fluid from the blood. It is calculated from the serum creatinine level using age and gender. Normal GFR can vary according to age (as you get older it can decrease). The normal value for GFR is 90 or above.

Detailed explanation-4: -The creatinine clearance test helps provide information about how well the kidneys are working. The test compares the creatinine level in urine with the creatinine level in blood. A measurement of the serum creatinine level is often used to evaluate kidney function.