NURSING ANM AND GNM

Detailed explanation-1: -A nonsense mutation occurs in DNA when a sequence change gives rise to a stop codon rather than a codon specifying an amino acid. The presence of the new stop codon results in the production of a shortened protein that is likely non-functional.

Detailed explanation-2: -Stop codons are also called nonsense codons because they do not code for an amino acid and instead signal the end of protein synthesis. Thus, nonsense mutations occur when a premature nonsense or stop codon is introduced in the DNA sequence.

Detailed explanation-3: -(NON-sens myoo-TAY-shun) A genetic alteration that causes the premature termination of a protein. The altered protein may be partially or completely inactivated, resulting in a change or loss of protein function.

Detailed explanation-4: -Nonsense codons are those that terminate the translation process since there are no corresponding tRNA molecules with anticodons for them. They are also called stop codons and there are three of them: UAA, UAG, UGA.

Detailed explanation-5: -A nonsense mutation also differs from a nonstop mutation, which is a point mutation that removes a stop codon.