NURSING ANM AND GNM

Detailed explanation-1: -Brain-wasting proteins called prions kill neurons by shortening the dendritic spines that the cells use to transmit signals to each other. Prions are infectious and cause neurodegenerative diseases such as scrapie in animals and Creutzfeldt–Jakob disease in humans.

Detailed explanation-2: -Prions are deadly pathogens that are notoriously difficult to inactivate, and standard microbial disinfection protocols are often inadequate. Recommended treatments for prion decontamination include strongly basic (pH ≥ 12) sodium hypochlorite bleach, ≥1 N sodium hydroxide, and/or prolonged autoclaving.

Detailed explanation-3: -Prions form abnormal aggregates of proteins called amyloids, which accumulate in infected tissue and are associated with tissue damage and cell death. Amyloids are also responsible for several other neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.