NURSING ANM AND GNM

Detailed explanation-1: -Abstract. The enzymatic polymerization of DNA and RNA is the basis for genetic inheritance for all living organisms. It is catalyzed by the DNA/RNA polymerase (Pol) superfamily.

Detailed explanation-2: -The first nucleotide polymerizing enzyme, DNA polymerase, was discovered in 1957. The free nucleotides that serve as substrates for this enzyme were found to be deoxyribonucleoside triphosphates, and their polymerization into DNA required a single-stranded DNA template.

Detailed explanation-3: -“DNA Polymerases are a group of enzymes that catalyse the synthesis of DNA during replication.” The main function of DNA polymerases is to duplicate the DNA content of a cell during cell division. They do so by adding nucleotides at 3’-OH group of the growing DNA strand.

Detailed explanation-4: -DNA polymerase catalyzes the formation of the phosphodiester bond by adding the deoxynucleoside triphosphate onto the growing polynucleotide chain. During this step-wise process, a single pyrophosphate molecule is released every time the chain is elongated by one deoxyribonucleotide.