NURSING ANM AND GNM

NURSING EXAM QUESTIONS

MICROBIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In course of long-term treatment of an infectious patient with penicillin, the pathogen transformed into the L-form. What changes occur in thepathogen cell in case of L-transformation?
A
Absence of a capsule
B
Absence of the cell wall
C
Absence of flagella
D
Absence of spores
Explanation: 

Detailed explanation-1: -Gram-negative bacteria attempting to grow and divide in the presence of peptidoglycan synthesis-inhibiting antibiotics (e.g. penicillin) fail to do so, and instead end up forming spheroplasts.

Detailed explanation-2: -Penicillin kills bacteria through binding of the beta-lactam ring to DD-transpeptidase, inhibiting its cross-linking activity and preventing new cell wall formation. Without a cell wall, a bacterial cell is vulnerable to outside water and molecular pressures, which causes the cell to quickly die.

Detailed explanation-3: -Amoxicillin covers a wide variety of gram-positive bacteria, with some added gram-negative coverage compared to penicillin. Like penicillin, it covers most Streptococcus species and is also effective against Listeria monocytogenes and Enterococcus species.

There is 1 question to complete.