NURSING ANM AND GNM

Detailed explanation-1: -Moderate changes in pH modify the ionization of amino-acid functional groups and disrupt hydrogen bonding, which, in turn, promotes changes in the folding of the molecule, promoting denaturation and destroying activity. The optimum growth pH is the most favorable pH for the growth of an organism.

Detailed explanation-2: -Acidophiles have optimal growth at pH values near 3 and alkaliphiles have optimal growth at pH values above 9. At the other end of the spectrum are alkaliphiles, microorganisms that grow best at pH between 8.0 and 10.5.

Detailed explanation-3: -How does pH negatively affect the metabolism of microorganisms? causes proteins and enzymes to denature and causing a loss of enzymantic activity.

Detailed explanation-4: -Most bacteria are neutrophiles, meaning they grow optimally at a pH within one or two pH units of the neutral pH of 7, between 5 and 8 (see Figure 9.35).