NURSING ANM AND GNM

Detailed explanation-1: -A prion /ˈpriːɒn/ ( listen) is a misfolded protein that can transmit its misfolded shape onto normal variants of the same protein. Prions are the causative agent of several transmissible and fatal neurodegenerative diseases in humans and other animals.

Detailed explanation-2: -Prions are misfolded proteins with the unique ability to do what most other proteins cannot: they can transmit their misfolded shape onto the correctly folded versions of the same protein.

Detailed explanation-3: -Transmissible spongiform encephalopathies (TSEs or prion diseases) are a rare group of invariably fatal neurodegenerative disorders that affect humans and other mammals. TSEs are protein misfolding diseases that involve the accumulation of an abnormally aggregated form of the normal host prion protein (PrP).

Detailed explanation-4: -Unlike other infectious agents, such as bacteria, viruses, and fungi, prions do not contain genetic materials such as DNA or RNA.

Detailed explanation-5: -RNA prions have two forms, a benign and a phenotype-causing one; analogously to the case of the protein prion [], conversion between the benign and prion form of RNA may involve RNA processing. The benign form may undergo a rare conversion to the prion form, perhaps stimulated by stress or other external factors.