NURSING ANM AND GNM

Detailed explanation-1: -If a mutation disrupts this normal reading frame, then the entire gene sequence following the mutation will be incorrectly read. This can result in the addition of the wrong amino acids to the protein and/or the creation of a codon that stops the protein from growing longer.

Detailed explanation-2: -Frameshift mutations are generally much more serious and often more deadly than point mutations. Even though only a single nitrogen base is affected, as with point mutations, in this instance, the single base is either completely deleted or an extra one is inserted into the middle of the DNA sequence.

Detailed explanation-3: -Frameshift mutations are among the most deleterious changes to the coding sequence of a protein. They are extremely likely to lead to large-scale changes to polypeptide length and chemical composition, resulting in a non-functional protein that often disrupts the biochemical processes of a cell.

Detailed explanation-4: -Frameshift mutations are usually some of the most harmful kinds of genetic mutations. In contrast to substitution or point mutations, which only affect one amino acid in the protein chain, frameshift mutations affect all the amino acids downstream of their location.