NURSING ANM AND GNM

NURSING EXAM QUESTIONS

MICROBIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
This feedback regulation in the branched pathway shows that individual end products have little or no negative inhibitory effect on the primary enzyme, but when these end-products function at the same time they act as potent inhibitors
A
sequential
B
cumulative or cooperative
C
compensatory antagonism
D
concerted or multivalent
Explanation: 

Detailed explanation-1: -Feedback inhibition is the situation where the end product of a biochemical pathway inhibits the activity of an enzyme catalyzing one of the reactions (normally the first reaction) of the pathway.

Detailed explanation-2: -Regulation on the physiological level of the pathways to the branched-chain amino acids occurs by the repression of the leucine and isoleucine-valine biosynthetic enzymes. A phenotypic derepression caused by valine was detectable in the case of the latter biosynthetic enzymes.

Detailed explanation-3: -Feedback inhibition of metabolic pathways In the process of feedback inhibition, the end product of a metabolic pathway acts on the key enzyme regulating entry to that pathway, keeping more of the end product from being produced.

Detailed explanation-4: -Feedback Inhibition in Metabolic Pathways Feedback inhibition is when a reaction product is used to regulate its own further production. Cells have evolved to use feedback inhibition to regulate enzyme activity in metabolism, by using the products of the enzymatic reactions to inhibit further enzyme activity.

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