NURSING ANM AND GNM

Detailed explanation-1: -Infection begins with ingestion of food or water contaminated with V. cholerae that goes on to colonize the small intestine and produce toxins. These toxins produce changes in the electrolyte channels causing massive fluid and electrolyte losses in the form of watery diarrhea.

Detailed explanation-2: -Cholera toxin is an exotoxin, so the question arises how is the toxin secreted out of the V. cholerae organism? The toxin has to cross both the inner and outer membranes to be secreted to the extracellular milieu. The mechanism of secretion has been well studied, and a number of proteins are involved in the process.