NURSING ANM AND GNM

Detailed explanation-1: -The Wassermann test or Wassermann reaction (WR) is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category.

Detailed explanation-2: -The Wassermann reaction was used in the diagnosis of syphilis. The antigen used in it was prepared empirically. Originally, the so-called antigens were extracts of human or monkey tissue rich in Treponema pallidum.

Detailed explanation-3: -The complement fixation test is a blood test that can determine the presence of antigen-specific antibodies by incubating patient serum with antigen and complement. This assay takes advantage of the requirement for complement to be activated by the combination of antigen-antibody complexes (Fig.

Detailed explanation-4: -For example, the Wasserman reaction is a diagnostic complement fixation test to detect antibodies to the syphilis-causing organism Treponema; a positive reaction indicates the presence of antibodies, and therefore syphilis infection.