NURSING ANM AND GNM

Detailed explanation-1: -Skin is a barrier that serves as one of the body’s first lines of defense against harmful microbes. Specialized immune cells within skin tissue help to fight invading organisms.

Detailed explanation-2: -Keratinocytes. Keratinocytes are the predominant cells in the epidermis. They act as the first line of innate immune defence against infection. They express Toll-like receptors (TLRs), which are pattern-recognition receptors (PRRs) that detect conserved molecules on pathogens and trigger an inflammatory response.

Detailed explanation-3: -Epithelial tissue, or skin, is an animal’s first line of defense against environmental challenges. It covers all exterior and interior surfaces of the body, like its cavities, tubes, organs and blood vessels, including the respiratory, reproductive, urogenital and gastrointestinal tracts.

Detailed explanation-4: -The epidermis, the outermost layer of the skin, is a physical barrier against pathogens.

Detailed explanation-5: -Physical and chemical barriers form the first line of defense when the body is invaded. The skin has thick layer of dead cells in the epidermis which provides a physical barrier.