NURSING ANM AND GNM

Detailed explanation-1: -These are called competitive inhibitors. They resemble the substrates in their structure. If they bind before substrates, the substrates cannot bind to enzymes. This results in competitive inhibition leading to blocking of the active site.

Detailed explanation-2: -If a chemical inhibits the enzyme by binding at the active site, that is a giveaway sign that the chemical is in the category of competitive inhibitors, as opposed to non-competitive inhibitors.

Detailed explanation-3: -Competitive inhibition happens when a compound similar to the substrate is present and competes with the substrate for the active sites of the enzyme obstructing the access of substrate to the active site, thus slowing down the reaction.

Detailed explanation-4: -Because the substrate cannot bind to an enzyme–inhibitor complex, EI, the enzyme’s catalytic efficiency for the substrate decreases. With noncompetitive inhibition the substrate and the inhibitor bind to different active sites on the enzyme, forming an enzyme–substrate–inhibitor, or ESI complex.