NURSING EXAM QUESTIONS
MICROBIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which enzyme begins DNA replication with a small strand of RNA?
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Helicase
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Primase
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DNA Ligase
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DNA Polymerase
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Explanation:
Detailed explanation-1: -Polymerase is found in a complex with primase, and it appears to function in conjunction with primase to synthesize short RNA-DNA fragments during lagging strand synthesis.
Detailed explanation-2: -Primase is the enzyme that synthesizes RNA primers. Primers are oligonucleotides that are complementarily bound to a DNA template and from which DNA polymerases elongate. Special proteins are responsible for loading primase at the origin of replication so that leading strand DNA synthesis can commence.
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