NURSING ANM AND GNM

Detailed explanation-1: -Cell damage can be reversible or irreversible. Depending on the extent of injury, the cellular response may be adaptive and where possible, homeostasis is restored. Cell death occurs when the severity of the injury exceeds the cell’s ability to repair itself.

Detailed explanation-2: -Two phenomena consistently characterize irreversible injury. The first is the inability to reverse mitochondrial dysfunction (lack of oxidative phosphorylation and ATP generation) even upon restoration of oxygen; the second is the development of profound disturbances in membrane function.

Detailed explanation-3: -Necrosis is a type of irreversible cell injury characterized by cytoplasmic swelling, damage to the plasma membrane and organelle destruction. All of which cause cell death.