NURSING ANM AND GNM

Detailed explanation-1: -Berson and Yalow were the first to develop an immunoassay, known as radioimmunoassay (RIA), for detecting endogenous plasma insulin [1], a development for which Yalow was awarded the Nobel Prize in Physiology or Medicine in 1977.

Detailed explanation-2: -She developed radioimmunoassay (RIA) together with doctor Solomon Berson. RIA is used to measure small concentrations of substances in the body, such as hormones in the blood. Yalow and Berson tracked insulin by injecting radioactive iodine into patients’ blood.

Detailed explanation-3: -Radioactive Labeling: Radioimmunoassay The most famous discovery made by Yalow and Berson was a technique called radioimmunoassay, or RIA, a method of quantifying minute amounts of biological substances in the body using radioactive-labeled material.

Detailed explanation-4: -The most commonly used radioisotope for RIA is an isotope of iodine called iodine-125 (125I). Iodine-125 offers several advantages, such as it can be prepared with very high specific activity and with almost 100% isotopic abundance.

Detailed explanation-5: -A radioimmunoassay (RIA) is an immunoassay that uses radiolabeled molecules in a stepwise formation of immune complexes. A RIA is a very sensitive in vitro assay technique used to measure concentrations of substances, usually measuring antigen concentrations (for example, hormone levels in blood) by use of antibodies.