NURSING EXAM QUESTIONS
PATHOLOGY AND GENETICS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Cross the placenta
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IgA
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IgD
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IgE
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IgG
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IgM
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Explanation:
Detailed explanation-1: -IgG antibodies can cross and do cross the placenta during pregnancy from the mother to the fetus. The passage starts by the end of the first trimester and continues throughout pregnancy. This is a manner by which the fetus gets passive humoral immunity from the mother.
Detailed explanation-2: -The efficiency of transplacental transfer of the different IgG subclasses was determined. Transfer of IgG1 and IgG4 was found to be significantly more efficient than that of IgG3 and IgG2. IgG2 was the subclass least efficiently transferred from mother to fetus.
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